Endocrine control of the intestinal calcium excretion.
نویسندگان
چکیده
Calcium excretion from rat intestine was measured by placing distilled water in an intestinal loop in situ and measuring the calcium content after various intervals. More calcium was excreted from the intestine of 18-month-old rats than that of 1-month-old rat. Acute hypocalcemia failed to change the intestinal calcium excretion significantly. Parathyroidectomy decreased intestinal calcium excretion and administration of Parathyroid Extract reversed it. Renal damage produced by injection of Na-sulfacetylthiazole increased the intestinal calcium excreation but dihydrotachysterol reversed it. Gastrin at 200 microng/kg increased the intestinal calcium excretion. Calcium excretion, like calcium absorption, appears to be controled by various endocrine factors and the method of intestinal loop in situ appears to be useful to study the part played by these factors.
منابع مشابه
Details of true calcium absorption and calcium excretion into feces in female rats during growth.
The details of calcium flux during growth were examined in female rats. Twenty-eight 53-d-old rats were equally divided into 4 groups. Rats were given a purified diet (0.5% Ca and 0.35% Pi) throughout the experiment. Calcium balance and 45Ca kinetics studies using an open two-compartment model were performed over a 3-d period when rats were 60 (control), 74 , 88 and 116 d old. A simple calcium ...
متن کاملGestational hypothyroidism-induced changes in L-type calcium channels of rat aorta smooth muscle and their impact on the responses to vasoconstrictors
Objective(s): Thyroid hormones play an essential role in fetal growth and maternal hypo-thyroidism which leads to cardiovascular deficiency in their offspring. Considering this, we intended to investigate the impact of gestational hypothyroidism on offspring vascular contractibility and possible underlying mechanisms. Materials and Methods: Hypothyroidism was induced in female rats by administ...
متن کاملThe effects of phosphorus depletion, and of calcium and phosphorus intake, on the endogenous excretion of these elements by sheep.
I . Injections of and 45Ca were used to study the influence of phosphorus depletion and repletion on the rates of endogenous calcium and P excretion in fifteen P-depleted and eighteen control sheep. 2. When given adequate P, there was a marked increase in the rate of excretion of metabolic faecal P in sheep which previously had been depleted. In control sheep a decrease was found in metabolic f...
متن کاملIncreasing the intestinal resistance of rats to the invasive pathogen Salmonella enteritidis: additive effects of dietary lactulose and calcium.
BACKGROUND AND AIMS Lactulose fermentation by the intestinal microflora acidifies the gut contents, resulting in an increased resistance to colonisation by acid sensitive pathogens. The extent of fermentation should be controlled to prevent acid induced epithelial cell damage. Considering the buffering capacity of calcium phosphate and its intestinal cytoprotective effects, whether supplemental...
متن کاملStudy on the effect of high calcium intake on serum protein bound iodine and urinary excretion of iodine
Iodine deficiency remains a major health problem in the world, including some parts of Iran. It has been recognized that there is usually a close and inverse relationship between iodine in the soil and water and presence of endemic goiter. Calcium has been suggested as one of goitrogens, though the definite role, extent and mechanism particularly in human have not been studied. Serum protein-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Endocrinologia japonica
دوره 24 1 شماره
صفحات -
تاریخ انتشار 1977